Surgical Management Of Maxillary Osteonecrosis Associated With Bisphosphonate Treatment: Case Report And Literature Review

¹ Department of Oral an Maxillofacial Surgery. Universitary Hospital “Virgen de las Nieves”. Granada.(Spain).

²Department of Healthcare . University of Granada (Spain).

³ Department of Surgery. Universitary Hospital “Virgen de las Nieves”. Granada.(Spain).

4 Department of Anestesiology. Universitary Hospital “Virgen de las Nieves”. Granada.(Spain).

Corresponding Author: Sánchez López. José Darío, Universitary Hospital “Virgen de las Nieves” Tel: 34-609628514; Email: [email protected]

Received Date: 22 Sep 2018  
Accepted Date: 06 Oct 2018  
Published Date: 10 Oct 2018 

Copyright © 2018 Darío SLJ

Citation: Darío SLJ, Paolo C, Jacobo CM, Mercedes VC, et al. (2018). Surgical Management Of Maxillary Osteonecrosis Associated With Bisphosphonate Treatment: Case Report And Literature Review. M J Surg. 2(1): 012.

ABSTRACT

The main aim of this paper is to show the management of a patient with advanced Bisphosphonate-related osteonecrosis of the maxillar (BRONM) and to provide a discussion of the alternatives for the treatment of this condition. We report the history of a 72-year-old-woman without any information of interest on her clinical records, who underwent breast cancer surgery on 2005 because of a ductal breast carcinoma. After surgery, it was decided to use chemo- and radiotherapy as an adjuvant treatment, adding intravenous bisphosphonates (BPs) to prevent bone metastasis. In the postoperative control thirteen years after the administration of BPs the patient evolution was torpid. A facial CT scan was performed showing an osteosclerosis and an isolated bone sequestration image compatible with the developing of advanced BRONM. It was decided to practice surgical treatment of the lesion, after treatment for three days with broad-spectrum antiobiotherapy. Risk factors of BRONM and surgical modalities of treatment are discussed.

KEYWORDS

Maxillary Osteonecrosis; Bisphophonates; Surgical Treatment.