Ferruccio Trifirò1,*, Paolo Zanirato2,#
1Professor Emeritus, University of Bologna, Italy
2Associate Professor, University of Bologna, Italy
*Corresponding author: Dr. Ferruccio Trifirò, Professor Emeritus, University of Bologna, Via Zamboni 31, Bologna, Italy, Phone: +39 3207987039, E-mail: ferruccio.trifiro@unibo.it
#Co-corresponding author: Dr. Paolo Zanirato, Associate Professor, University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy, Phone: +39 3391051242, E-mail: paolo.zanirato@unibo.it
Received Date: March 01, 2025
Published Date: March 24, 2025
Citation: Trifirò F, et al. (2025). Catalytic Options for Pharmaceuticals from CPhI Some Solutions to Problems. Mathews J Pharma Sci. 9(2):47.
Copyrights: Trifirò F, et al. © (2025).
ABSTRACT
At the Pharmaceutical Industry Ingredients Fair (CPhI), some solutions to the problems that catalysis encounters in its use in the production of drugs, as an alternative to traditional synthesis, were presented. New ligands were developed that increased the activity, chemo and enantioselectivity of homogeneous catalysts, and allowed their heterogeneization, and technologies for their recovery from reaction solutions and new supports to make heterogeneous catalysts more filterable. At the CPhI fair in Madrid, November 2005, the innovation prizes were awarded to three companies that have brought the results of their research to an industrial level: Accentus for a predictive technique and fast screening of crystallization processes (1st prize), Lanxess for the stereospecific fluorination of chiral alcohols (2nd prize) and Novasep for the advancement of chromatographic separation technology that uses supercritical CO2 as an eluent (III° award).
Keywords: Pharmaceutical Industry Ingredients Fair (CPhI), Chemo, Enantio-Selectivity Homogeneous Catalysts, Crystallization Processes, Chromatographic Separation Technology.