Mathews Journal of Pharmaceutical Science

2474-753X

Previous Issues Volume 7, Issue 1 - 2023

A Review on Formulation and Evaluation Approaches for Fast Release Tablet

Prashant Upadhyay*, Kalpana, Priya Chaudhary, Sukirti Upadhyay

School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India
*Corresponding author: Prashant Upadhyay, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India; Tel: 9719915567; Email: [email protected]

Received Date: 09 Jan 2023

Published Date: 25 Jan 2023

Citation: Upadhyay P, et al. (2023). A Review on Formulation and Evaluation Approaches for Fast Release Tablet. Mathews J Pharma Sci.  7(1):15.

Copyrights:  Upadhyay P, et al. © (2023). 

ABSTRACT

Among all forms of volume, the tablet is the most popular volume method available today due to its convenience of self-control, coherence and easy production; sometimes immediate relief the onset of action is necessary than conventional treatment in most cases. To overcome these barriers, a form of immediate release dose has emerged like other oral dose forms. Forms of rapid drug release dispersal immediately after treatment with an improved degree of elimination. The basic method used in pill development is the use of superdisintegrants such as Kyron T-314 based on polymer bonded Polycarboxylic acid per USP/NF and has a K+ionic form. The Kyron T-316 is a relatively new fast disintegration system specifically for acid-containing drugs that promote dispersion and dissolution. Sodium starch glycolate (Primogel, Explotab), carboxymethyl cellulose (Croscarmellose) etc. The drug categories selected for immediate release are painkillers and anti-inflammatory drugs such as Ibuprofen, Diclofenac sodium. Anti-coagulants such as Dicoumarol, Dipyridamol. Anti-Depressants like Amoxapiine. Antidiabetic as Glipizide. Antibacterial like Linezolid, antihypertensive drugs like Amlodipine, Minoxidil, Nifedipine are best for immediate release.

Keywords:  Fast release, Polymers, Super disintegrants, Kyron T-314 And 316, Wet Granulation, Release Kinetics


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