Evaluation of In-vitro Angiotensin Converting Enzyme (ACE) Property of (Balanites aeqyptiaca. Del) Meal, Defatted Meal, Concentrate and Hydrolysates

¹Department of Home Sciences, Faculty of Agriculture, Federal University, Gashua, P.M.B.1005 Gashua, Yobe State, Nigeria

²Department of Food Science and Technology, Federal University of Agriculture, Makurdi, Benue State, Nigeria

*Corresponding author: Ogori Akama Friday, Department Of Home Science And Management, Faculty Of Agriculture, Federal University, Gashua, P.M.B.1005 Gashua, Yobe State, Nigeria; Tel: 08070626328, 07085100611; E-mail: [email protected].

Received Date: December 09, 2022

Published Date: January 03, 2023

Citation: Friday OA, et al. (2023). Evaluation of In-vitro Angiotensin Converting Enzyme (ACE) Property of (Balanites aeqyptiaca. Del) Meal, Defatted Meal, Concentrate and Hydrolysates. Mathews J Nutr Diet. 6(1):21.

Copyrights: Friday OA, et al. © (2023).

ABSTRACT

Edible seed proteins stand greater chance to manage chronic diseases. Balnites aegyptiaca seed is widely natural across Africa and in Asian countries. This desert three seed nut has potential nutritional properties which are been utilized at home nowadays. This study was to determine the in vitro ACE potentials of Aduwa protein meals and hydrolysate. Aduwa seeds were toasted at 70 °C, milled and oil extracted to make APM. The meal was defatted made into concentrate and finally into hydrolysates. The hydrolysate was hydrolyzed by using pepsin, pancreatin, pepsin and pancreatin combines protease. The samples were subjected to different inhibitory concentration EC₅, EC₁₀ and EC₂₀ invitro angiotensin converting enzyme activities. The result revealed that Aduwa meal protein and hydrolysate has the potential to reduce blood pressure. The resolved meals exhibited greater angiotensin converting enzyme activities at five inhibitory concentrations (EC₅₎ respectively, for defatted meal was (5%), concentrate (3%) pancreatin hydrolysate (4%), pepsin hydrolysate (2%) and combined hydrolysate (2%). Inhibition concentration at EC₁₀ exhibited significant high angiotensin converting enzyme activities value in defatted meal and pancreatin hydrolysate when compared with the referral control. The results suggested that defatted meal, pancreatin hydrolysate at EC₁₀ and pepsin hydrolysate at EC₅ and EC₂₀ respectively had better invitro angiotensin converting enzyme inhibitory potentials, hence Aduwa seed protein bioactive has inhibitory potentials to act as antihypertensive agents that could be utilized as ingredients for the development of novel functional foods and nutraceuticals in future.

Keywords: Aduwa Seed, Meals, Protein Concentrate, Protein Hydrolysates, Inhibition Concentration, ACE Inhibition.