Patients with a Diagnosis of Malignant Cancer First After Tia/Stroke Usually Appear to Have Lower Annual Risk of Stroke/Myocardial Infarction Events Compared to Patients Without Cancer Diagnosis. A 25-Year Follow-Up Hospital-Based Observational Study

Division of Neurology, Department of Medicine, Falun Hospital, S-791 82 Falun, Sweden

Corresponding Author: Sven-Erik Eriksson, Division of Neurology, Department of Medicine, Falun Hospital, S-791 82 Falun, Sweden, Tel: +46 70-5717116; E-Mail: [email protected]

Received Date: 15 Mar 2018  
Accepted Date: 20 Mar 2018  
Published Date: 22 Mar 2018
Copyright © 2018 Sven-Erik E

Citation: Sven-Erik E. (2018). Patients with a Diagnosis of Malignant Cancer First After Tia/Stroke Usually Appear to Have Lower Annual Risk of Stroke/Myocardial Infarction Events Compared to Patients Without Cancer Diagnosis. A 25-Year Follow-Up Hospital-Based Observational Study. Mathews J Neurol. 3(1): 010.

ABSTRACT

Background and aim: To assess whether transient ischaemic attacks (TIA)/stroke patients with a diagnosis of malignant cancer at any time of life had different prognoses regarding annual risk of stroke/myocardial infarction (MI) or survival compared to TIA/stroke patients without cancer.

Material and methods: A retrospective study of transient ischaemic attacks (TIA)/stroke patients hospitalized in the Stroke Unit or in the Department of Neurology, Linkoping, in 1986 and followed up to Feb. 2011.

Results: In total, 67 of 288 men (23%) had 78 cancers, and 69 of 261 women (26%) had 72 cancers. The type of cancer, past cancer or not, and patient sex were each important factors in the annual risk of stroke or MI. New stroke was a statistically significantly more common cause of death in the group of male patients who did not have a malignant cancer (p=.004), as was fatal MI in women (p=.016). There were no statistically significant differences in survival in men or women with cancer vs. without cancer.

Conclusion: This study provides support for the assumption that cancer itself and/or its treatment may have impact on stroke/myocardial infarction events in patients with TIA/stroke.

KEYWORDS

Cancer; Myocardial Infarction; Recurrent Stroke; Survival.