A Case of Post-Lyme Disease Syndrome (PLDS) Involving Motor Neuropathy and Myositis

Department of Neurology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

Corresponding Author: Yuka Shirai and Yuko Shimizu, Department of Neurology, Tokyo Women's Medical University 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan, Tel: +81-3-3353-8111; E-Mail: [email protected],  [email protected]

Received Date: 02 Jan 2018  
Accepted Date: 17 Jan 2018  
Published Date: 19 Jan 2018
Copyright © 2018 Shirai Y and Shimizu Y

Citation: Shirai Y, Shimizu Y, Uchiyama Y, Kobayashi M, et al. (2018). A Case of Post-Lyme Disease Syndrome (PLDS) Involving Motor Neuropathy and Myositis . Mathews J Neurol. 3(1): 009.

ABSTRACT

A 53-year-old man presented with bilateral foot drop. His lower-extremity weakness predominantly affected the distal right limb. He presented hypercreatine kinasemia and high antibody titer for Borrelia species (spp). The nerve conduction study and needle electromyography suggested active neurogenic findings, indicating motor neuropathy. The gastrocnemius muscle biopsy showed scattered fiber necrosis and inflammatory cell infiltration, representing myositis. After administration of minocycline, Borrelia spp antibodies became negative. Symptoms gradually improved with repeated intravenous immunoglobulin administration. This is a very rare case of post-Lyme disease syndrome involving motor neuropathy and myositis, which represents an immune-mediated reaction to Borrelia spp infection

KEYWORDS

Post-Lyme Disease Syndrome; Motor Neuropathy; Myositis; Intravenous Immunoglobulin Administration; Borrelia Infection; Intravenous Immunoglobulin.