Leucocytes and CD4 Counts of Individuals Exposed to Roadside Dust in Ekpoma, Edo State, Nigeria

¹Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria

²Department of Medical Microbiology, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria

*Corresponding author: Babatope IO, Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Nigeria, Tel: +2348022303311, Email: [email protected]

Received Date: June 15, 2024

Published Date: September 14, 2024

Citation: Babatope IO, et al. (2024). Leucocytes and CD4 Counts of Individuals Exposed to Roadside Dust in Ekpoma, Edo State, Nigeria. Mathews J Immunol Allergy. 8(2):29.

Copyrights: Babatope IO, et al. © (2024).

ABSTRACT

Roadside dust is a combination of particulate matter generated from vehicular traffic and other human activities along the road. This study investigated the leucocytes and Cluster of Differentiation-4 (CD4) counts of individuals exposed to roadside dust in Ekpoma, Edo State. A total to 50 test subjects aged 18-65 years and of both sexes were recruited for this study, while 50 individuals not exposed to road-side dust served as controls. The leucocytes and CD4 counts were analyzed using Sysmex KX-21N Autoanalyzer and Flow cytometry method respectively. The results obtained revealed the total white blood cell counts of the subjects studied were 5.27±1.60 and 5.22±1.66 for the test and control subjects respectively. With respect to the differential leucocyte count, the mean values of the test and control subjects for NEUT %, LYM % and MXD % were 40.31±9.75 and 38.62±10.0, 47.9±9.15 and 50.7±9.86, 11.66±4.40 and 10.7±3.72 respectively. Furthermore, the mean values of the CD4 counts of the test and control subjects were 890.26±266.21 and 850.94±302.13 respectively. Statistical comparison of the mean values of total WBC, differential leucocytes count and CD4 counts and road side dust did not reveal any significant difference (p>0.05). With respect to age, gender and duration of exposure to road-side dust, the leucocytes and CD4 counts were not significantly affected. In conclusion, exposure to road dust did not affect the leucocytes and CD4 counts of our study subjects.

Keywords: Leucocytes, CD4, Roadside, Dust, Haematology.