Type 2 Diabetes: Modulation of Metabolism, Cell Therapy and Other Options Beyond Insulin Therapy

¹Stem Cells and Regenerative Medicine Centre, Yenepoya Research Centre, Yenepoya University, Mangalore-575 018, Karnataka, India.

Corresponding Author: Bipasha Bose, Stem Cells and Regenerative Medicine Centre, Yenepoya Research Centre, Yenepoya University, Mangalore-575 018, Karnataka, India, Tel:+49-(0)89-2180-1617; E-Mail: [email protected]

Received Date: 28 Jun 2016  
Accepted Date: 25 Jul 2016   
Published Date: 26 Jul 2016

Copyright © 2016 Bose B

Citation: Bose B. (2016). Type 2 Diabetes: Modulation of Metabolism, Cell Therapy and Other Options Beyond Insulin Therapy. Mathews J  Diabetes Obes. 1(1): 002.

ABSTRACT

Type 1 diabetes is often hereditary, but type 2 diabetes is primarily lifestyle dependent. The world is currently threatened by the ever increasing trend of T2D that is also associated with diabetes-associated complications such as heart disease, diabetic nephropathy, diabetic retinopathy and so on. As 85-90% of all the diabetes cases in the world are T2D, it becomes all the more important to find avenues to cure T2D. Lifestyle dependency of T2D presents as insulin resistance. Hence, conversion of insulin resistant state to an insulin sensitive state is an essential process for mitigation of this lifestyle associated disorder. Insulin administration is the standard therapy for all kinds of diabetes that has been recently proven to be a contributor to obesity. However, in the case of T2D lifestyle management is more important. This short review focuses on other modalities of managing T2D with or without combining conventional insulin therapy primarily modulation of metabolism using various options, in addition to, diet and exercise.

KEYWORDS

Type 2 diabetes; Incretin; Cell therapy; Leptin; Brown adipose.