¹Dentist, Faculty of Dentistry, University of Carabobo, Valencia, Venezuela.

²Specialist in Oral Surgery Central University of Venezuela, Venezuela.

³Maxillofacial Surgery Care Residence, Ángel Larralde University Hospital, Carabobo, Venezuela.

*Corresponding Author: Luis Gerardo Montoya Davila. Dentist (DMD), Faculty of Dentistry, University of Carabobo, Valencia, Venezuela. Imaging Technologist, University Arturo Michelena, San Diego, Venezuela. Mailing Address: 5501 Glenridge Dr, Atlanta, Georgia-30342, USA. Tel: +1 (857) 347-1289, ORCID: 0000-0001-8332-2424, Email: [email protected]

Received Date: November 06, 2024

Published Date: December 02, 2024

Citation: Montoya LG, et al. (2024). Comparison of the Effectiveness of Platelet-Rich Fibrin and Hyaluronic Acid Injections on the Pain Management of Temporomandibular Joint Disorder. Mathews J Dentistry. 8(4):55.

Copyrights: Montoya LG, et al. © (2024).

ABSTRACT

Background: There are different treatments for painful temporomandibular joint dysfunction (TMD), one of them is intra- articular injection in moderate to severe cases. Purpose: The study aimed to compare the effectiveness of the use of platelet-rich fibrin and Hyaluronic Acid injections to treat painful TMD, both accompanied by traditional treatment with an occlusal splint (OS). Study Design, Setting, Sample: This is a prospective, quasi-experimental research study with a pretest-posttest with a control group design. A non-probabilistic sample was taken with subjects recruited from authors' private practices from June 2023 to September 2023. The eligibility criteria for this study were adults with pain level at the TMJ equal or higher than 6 according to the Numerical Pain Rating Scale (NPRS). Predictor/Exposure/Independent Variables: The predictor variables were the injection treatments using Platelet Rich in Fibrin in conjunction with OS and Hyaluronic Acid in conjunction with OS. These were randomly assigned to subjects, each one of them representing a group for comparison purposes. Main Outcome Variables: Painful dysfunction was evaluated using the NPRS scale reported by subjects in-person visits throughout the 45 days treatment. Covariates: Demographic variables such as age and sex were considered for this study. Analyses: Descriptive data were represented using mean and standard deviation (SD). The data was compared using ANOVA test with statistical significance situated at <0.05. This was accompanied by Post Hoc analysis. Results: The study sample consisted of 60 subjects divided into three groups: PRF group with OS, HA group with OS, and OS by itself as the control group. 76% were female and with a mean age of 38 ±15.85. The results obtained showed the PRF in conjunction with OS treatment was the most effective; achieving a pain resolution within the 1st appointment in 70% of the subjects tested. Statistical significance was found in this regard among groups (F = 0.212 and P value = 0.000). Conclusions: While all treatments relieve the painful symptoms of the TMJ dysfunction, the PRF plus OS is the most effective and has the best, fastest results in resolving pain.

Keywords: Temporomandibular Joint Disorders, Platelet- Rich Fibrin, Hyaluronic Acid, Occlusal Splints.