Semen Profile Quality and Serum Hormonal Profile Relationship Among Infertile Men Attending General Hospital Awo Omamma, Imo State

¹Department of Microbiology, Faculty of Sciences, Imo State University Owerri, Imo State, Nigeria

²Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Nigeria

³Department of Laboratory Services, General Hospital Awo Omamma, Imo State, Nigeria

*Corresponding Author: Johnkennedy Nnodim, Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Nigeria, Phone: 08181366290, Email: [email protected]

Received Date: November 21, 2024

Published Date: December 20, 2024

Citation: Njoku-Obi T, et al. (2024). Semen Profile Quality and Serum Hormonal Profile Relationship Among Infertile Men Attending General Hospital Awo Omamma, Imo State. Mathews J Case Rep. 9(10):193.

Copyrights: Njoku-Obi T, et al. (2024).

ABSTRACT

 Semen profile and hormone profile are important parameters in giving a good diagnosis in male infertility. dysfunction of hormone production has been noted as a causative factor in male. This study was carried out to determine the semen profile including semen count, motility, volume, viscosity as well as morphology of semen and the hormone profile including Testosterone, Follicular stimulating hormone (FSH)) and Prolactin (PRL)) among infertile Awo Omamma males in Imo State. A total of 100 fertility dysfunction men were recruited to participate in this study. Semen sample was collected from each participant either by masturbation or coitus interruptus in a sterile container. One hundred venous bloods were collected under aseptic condition into heparinized container for hormonal profile analysis. The (FSH), Testosterone, Follicular stimulating hormone (FSH)) and PRL levels were measured quantitatively for each sample using automated immunoassay analyzer. The serum level of FSH (37.53±4.81ng/ml) and prolactin (453.71±34.18ng/ml) in infertile men were significantly increased when compared to non-infertile men (8.32±4.88ng/ml and 84.10±23.74ng/ml) respectively at P < 0.05. The serum level of Testosterone (6.92±2.90 ng/ml) was significantly decreased in infertile men when compared with control (9.01±3.11ng/ml) (P < 0.05). The hormone profile levels (FSH, Prolactin and testosterone) were within the normal reference value among the group of secondary fertility and fertility checkup males. Hormonal evaluation must be done as part of the routine diagnosis of male infertility as their levels were dependent on quality of semen profile.

Keywords: Hormonal Tests, Semen Profile, Infertility, Awo Omamma, Imo State.