Langerhans Cell Histiocytosis (LCH) of the Sacrum: Report of Two Cases

¹Consultant, Orthopedic Spine Surgeon & Scoliosis, Pediatric Orthopedics, Musculoskeletal Oncology, Private practice, King Hussain Cancer Center, Amman, Jordan

²Orthopedic Fellow, King Husain Cancer Center, Amman Jordan

³Medical Student Alexandria Medical School, Alexandria, Egypt

*Corresponding author: Alfawareh Mohammad, Consultant, Orthopedic Spine Surgeon & Scoliosis, Pediatric Orthopedics, Musculoskeletal Oncology, Private practice, King Hussain Cancer Center, Amman, Jordan; Email:[email protected]

Received Date: March 20, 2023

Publication Date: April 11, 2023

Citation: Mohammad A, et al. (2023). Langerhans Cell Histiocytosis (LCH) of the Sacrum: Report of Two Cases. Mathews J Case Rep. 8(4):101.

Copyright: Mohammad A, et al. © (2023)

ABSTRACT

Eosinophilic granuloma of bone (EG) also called Langerhans cell Histiocytosis (LCH) is a benign tumor-like condition, is a relatively rare disorder of unknown etiology, characterized by clonal proliferation of Langerhans-type Histiocytosis in the bone or lung [1]. EG most commonly affects children 5 to 10 years of age, 90% occurs under the age of 15 b [2]. LCH can involve any of the body tissues. The occurrence of LCH in the sacrum is extremely rare, LCH location and the number of lesions determine its mortality and morbidity potentials. The current study reports two cases of LHD involving the sacrum, both less than the age of 5, one of them presented with a significant neurological deficit and both were managed conservatively.

Keywords: Langerhans Cell Histiocytosis, eosinophilic granuloma, Bone, Hand-Schüller-Christian disease, autistic disorder