Cytokine-induced Neurogenesis for the Prevention and Treatment of Alzheimer’s Disease

¹Ochanomizu Health and Longevity Clinic, Tokyo 101-0062, Japan

²Shirasawa Anti-Aging Medical Institute, Tokyo 101-0062, Japan

³Livant Neurorecovery Center, Guadalajara, Mexico

*Corresponding Author: Takuji Shirasawa, Ochanomizu Health and Longevity Clinic, Tokyo 101-0062, Japan & Shirasawa Anti-Aging Medical Institute, Tokyo 101-0062, Japan, Email: [email protected]

Received Date: October 21, 2024

Published Date: October 31, 2024

Citation: Shirasawa T, et al. (2024). Cytokine-induced Neurogenesis for the Prevention and Treatment of Alzheimer’s Disease. Mathews J Case Rep. 9(9):187.

Copyrights: Shirasawa T, et al. (2024).

ABSTRACT

Alzheimer’s disease (AD) is a progressive neurodegenerative disease for which no curative treatment has been established. We administered cytokine-induced neurogenesis treatment combined with a ketogenic and elimination diet to a 66-year-old male AD patient carrying APOE ε4/ε4 alleles to regenerate residual neuronal stem cells. The treatment resulted in the successful regeneration of the atrophied hippocampus, which was associated with improved cognitive function and the resolution of electrophysiological abnormalities. We analyzed food allergies to identify the modifiers that influence AD progression. A food allergy analysis panel revealed that the specific IgG antibodies for casein, cow milk, and whey were positive, whereas the specific IgG antibody for gluten was negative; these allergies were improved by the ketogenic and elimination diet and associated with improved cognition.

Keywords: Alzheimer’s Disease (AD), APOE, Cytokine, Neurogenesis, Food Allergy, Molecular Chaperone, Ketogenic Diet.