A Comprehensive and Clinical Review of Chromosome 9 Ring Syndrome

Medical Genetics-Harvard University. Director of the Division of Medical Genetics and Molecular Optogenetic Research. Division of Medical Genetics and Molecular Pathology Research, Harvard University, Boston Children's Hospital, USA

*Corresponding Author: Shahin Asadi, Medical Genetics-Harvard University. Director of the Division of Medical Genetics and Molecular Optogenetic Research.Division of Medical Genetics and Molecular Pathology Research, Harvard University, Boston Children's Hospital, USA; Email: [email protected]

Received Date: April 12, 2023

Publication Date: April 17, 2023

Citation: Montazeri, et al. (2023). A Comprehensive and Clinical Review of Chromosome 9 Ring Syndrome. Mathews J Case Rep. 8(5):107.

Copyright: Montazeri M, et al. © (2023)

ABSTRACT

Ring chromosome 9 syndrome is a rare chromosomal disorder in which the two ends of chromosome number 9 are lost and the two ends connect to each other and form a ring. Associated symptoms and findings may vary depending on the amount and location of missing chromosomal material and other factors. As mentioned above, ring chromosome 9 syndrome may be characterized by various craniofacial abnormalities. However, in some cases, such features may not be obvious. Cranial and facial defects associated with ring chromosome 9 syndrome may include abnormally small head size (microcephaly) or premature fusion of the fibrous joint (suture) between the bones that make up the forehead (metopic suture), resulting in a narrow forehead. Ring chromosome 9 syndrome is caused by the removal of chromosomal material from the end (distal) regions of the short arm (p) and long arm (q) of chromosome number 9 and connecting its ends to form a ring. Chromosomes are found in the nucleus of all cells in the body. They have the genetic characteristics of each person.

Keywords: Ring chromosome 9 syndrome, Chromosome Abnormality, Genetics Disorders