SARS-CoV-2 Vaccination Induced Pericarditis and Myocarditis

Department of Pediatrics, Columbia University Irving Medical Center, USA

*Corresponding Author: Thyyar M Ravindranath, MD, Senior Lecturer, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Morgan Stanley Children’s Hospital of NewYork-Presbyterian, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, 630 West 168th Street, New York, New York-10032, USA, E-mail: [email protected]

Received Date: May 16, 2024

Published Date: June 13, 2024

Citation: Ravindranath Thyyar M. (2024). SARS-CoV-2 Vaccination Induced Pericarditis and Myocarditis. Mathews J Cardiol. 8(2):37.

Copyrights: Ravindranath Thyyar M. © (2024).

ABSTRACT

Cardiac inflammation in the form of myopericarditis (myocarditis and pericarditis) is a well-known and rare complication of the SARS-COV-2 (COVID-19) vaccination for both the mRNA constructed as well as the Adeno viral based platforms. Myopericarditis following COVID-19 vaccination is a transient phenomenon with very low morbidity and mortality is rare. A high degree of suspicion in younger, vaccinated individuals in the appropriate clinical setting and confirmatory laboratory evaluation leads to the diagnosis. The treatment approach is based on the presence of symptoms and the outcome is excellent although the long-term outlook is unknown at present. In this brief review, the mechanism of action of mRNA and vector based COVID-19 vaccines, the proposed mechanism of pathogenesis of cardiac inflammation following COVID-19 vaccination, diagnosis, therapeutic options, and follow up of patients will be discussed.

Keywords: SARS-COV-2 (COVID-19), Myopericarditis, Inflammation, Virus, Cytokines, Immunity.